Laboratory Services

Enumeration of Epithelial and Mesenchymal CTC Populations

CelLBxHealth has a standardized and fully integrated workflow for the enumeration and evaluation of epithelial and mesenchymal CTCs and CTC clusters.

The workflow integrates:

  • CelLBxHealth’s Parsortix Platform for CTC capture (capturing both epithelial and mesenchymal phenotypes), together with;
  • An optimized and customizable panel of antibodies for identification of the full range of CTCs (and exclusion of WBC), and;
  • Bioview imaging solutions for the evaluation and enumeration of CTCs

How the service works

Scientist holding blood sample
1

Whole Blood Sample

Send your patient blood samples to our laboratory.

Blood processing in a lab
2

Sample Processing

Samples will be processed by CelLBxHealth within 24 hours.

3

Image Capture

Images of captured and characterized CTCs shared via secure cloud.

4

Data Report

Report for each sample processed is shared back with you.

CelLBxHealth is able to include specific protein markers according to your needs.

The performance of the Parsortix Platform has been demonstrated in multiple third-party and peer reviewed publications. We would be pleased to share exemplary data obtained from our integrated enumeration workflow.

Example Images from Patient Blood Samples

Cluster of CK + CTCs (green) from breast cancer patient (20x)

Cluster of epithelial CTCs (green) from breast cancer patient (20x)

Cluster of CK+ (green) and mesenchymal (red) CTCs from breast cancer patient (20x)

Breast cancer CTC cluster containing epithelial, mesenchymal and epithelial-to
mesenchymal transition (EMT) phenotypes. Nuclear (blue), epithelial (green), mesenchymal (red), EMT (yellow/orange), blood cell (white).

CK + CTC from breast cancer patient (40x)

Epithelial CTC from breast cancer patient (40x)

Cluster of mesenchymal CTCs (red) from breast cancer patient (20x)

Cluster of mesenchymal CTCs (red) from breast cancer patient (20x)

Discover how CelLBxHealth can help with your liquid biopsy needs

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Research Use Only. Not for use in Diagnostic Procedures

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